2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. Discoidin Domain Receptor
  5. Discoidin Domain Receptor Isoform
  6. Discoidin Domain Receptor Degrader

Discoidin Domain Receptor Degrader

Discoidin Domain Receptor Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-176184
    PROTAC DDR1 degrader-1
    		Degrader
    PROTAC DDR1 degrader-1 is a PROTAC based DDR1 degrader (Red: DDR1 inhibitor (HY-176185), black: linker, Blue: E3 ligase ligand).
  • HY-162540
    LLC355
    		Degrader
    LLC355 is a discoidin domain receptor 1 (DDR1) ATTEC degrader. LLC355 efficiently degrades DDR1 protein with a DC50 value of 150.8 nM in non-small cell lung cancer NCI-H23 cells. LLC355 induces DDR1 degradation via lysosome-mediated autophagy. LLC355 potently inhibits cancer cell tumorigenicity, migration, and invasion.